Giornata 16
		45'	90'
10/12/21 18:00	Altay - Hatayspor	1 - 1	1 - 2
11/12/21 11:30	Fatih Karagümrük - Konyaspor	1 - 1	1 - 4
14:00	Çaykur Rizespor - Göztepe	1 - 0	3 - 1
	İstanbul Başakşehir - Kasımpaşa	0 - 0	2 - 1
17:00	Antalyaspor - Trabzonspor	1 - 1	2 - 1
12/12/21 11:30	Adana Demirspor - Giresunspor	0 - 0	1 - 0
14:00	Yeni Malatyaspor - Alanyaspor	2 - 3	2 - 6
17:00	Beşiktaş - Kayserispor	1 - 1	4 - 2
13/12/21 16:00	Sivasspor - Galatasaray	0 - 0	1 - 0
18:30	Gaziantep BB - Fenerbahçe	1 - 1	3 - 2

Giornata 17
		45'	90'
17/12/21 18:00	Giresunspor - Altay	1 - 0	3 - 1
18/12/21 11:30	Kasımpaşa - Sivasspor	1 - 0	1 - 3
14:00	Konyaspor - Antalyaspor	0 - 0	1 - 0
	Trabzonspor - Hatayspor	2 - 0	2 - 0
17:00	Alanyaspor - Adana Demirspor	1 - 2	1 - 3
	Galatasaray - İstanbul Başakşehir	0 - 1	1 - 1
19/12/21 11:30	Çaykur Rizespor - Yeni Malatyaspor	0 - 0	1 - 0
14:00	Göztepe - Fatih Karagümrük	0 - 0	0 - 1
	Kayserispor - Gaziantep BB	0 - 0	0 - 0
17:00	Fenerbahçe - Beşiktaş	2 - 1	2 - 2

Giornata 18
		45'	90'
21/12/21 15:00	Antalyaspor - Kasımpaşa	1 - 0	1 - 1
	İstanbul Başakşehir - Giresunspor	1 - 1	3 - 1
18:00	Adana Demirspor - Galatasaray	0 - 0	2 - 0
	Altay - Trabzonspor	1 - 0	1 - 2
22/12/21 15:00	Hatayspor - Konyaspor	1 - 1	1 - 3
	Sivasspor - Çaykur Rizespor	0 - 0	1 - 1
18:00	Fatih Karagümrük - Fenerbahçe	1 - 1	1 - 1
	Gaziantep BB - Alanyaspor	0 - 0	2 - 1
23/12/21 15:00	Yeni Malatyaspor - Kayserispor	2 - 0	2 - 2
18:00	Beşiktaş - Göztepe	1 - 1	2 - 1

Classifica

Squadra	Totali								In Casa					In Trasferta
Squadra	G	Punti	Media Punti	V	N	P	GF	GS	V	N	P	GF	GS	V	N	P	GF	GS
Trabzonspor	17	42	2,47	13	3	1	34	13	6	2	0	17	6	7	1	1	17	7
Konyaspor	17	33	1,94	9	6	2	28	14	6	3	0	16	6	3	3	2	12	8
İstanbul Başakşehir	17	29	1,71	9	2	6	26	18	6	1	2	14	7	3	1	4	12	11
Hatayspor	17	29	1,71	9	2	6	25	20	5	1	2	15	9	4	1	4	10	11
Fenerbahçe	17	28	1,65	8	4	5	28	22	4	3	1	16	9	4	1	4	12	13
Alanyaspor	17	27	1,59	8	3	6	27	28	4	1	3	15	13	4	2	3	12	15
Adana Demirspor	17	26	1,53	7	5	5	24	21	4	2	2	10	5	3	3	3	14	16
Sivasspor	17	25	1,47	6	7	4	25	16	3	5	1	15	7	3	2	3	10	9
Beşiktaş	17	25	1,47	7	4	6	28	26	6	1	2	19	13	1	3	4	9	13
Fatih Karagümrük	17	25	1,47	7	4	6	24	25	3	3	2	13	11	4	1	4	11	14
Galatasaray	17	24	1,41	6	6	5	22	21	4	2	2	11	8	2	4	3	11	13
Giresunspor	17	22	1,29	6	4	7	18	15	4	2	3	11	8	2	2	4	7	7
Gaziantep BB	17	22	1,29	6	4	7	21	25	6	2	0	16	6	0	2	7	5	19
Antalyaspor	17	21	1,24	6	3	8	20	24	5	1	3	15	11	1	2	5	5	13
Kayserispor	17	20	1,18	5	5	7	22	26	4	3	1	12	5	1	2	6	10	21
Altay	17	18	1,06	5	3	9	22	28	3	1	4	10	11	2	2	5	12	17
Çaykur Rizespor	17	16	0,94	5	1	11	16	32	5	1	3	12	9	0	0	8	4	23
Göztepe	17	14	0,82	3	5	9	16	25	2	1	6	5	11	1	4	3	11	14
Yeni Malatyaspor	17	14	0,82	4	2	11	14	30	2	1	6	11	22	2	1	5	3	8
Kasımpaşa	17	11	0,65	2	5	10	16	27	2	3	4	12	14	0	2	6	4	13